Beilstein J. Org. Chem.2011,7, 1141–1149, doi:10.3762/bjoc.7.132
run-to-run reproducibility of the H-Cube® reactor for screening and reaction optimization is discussed.
Keywords: catalyst leaching; CatCart®; H-Cube®; packedbedflowhydrogenation; Introduction
The potential advantages of heterogeneous catalytic flow hydrogenation over traditional batch reactor
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Graphical Abstract
Scheme 1:
Reduction of 4-(4-azidopiperidin-1-yl)benzonitrile on the H-Cube®.